§ 403.13. Non-steroidal anti-inflammatory drugs.
The use of Non-Steroidal Anti-Inflammatory drugs (NSAID) shall be governed by the following conditions:
(a) NSAIDs included in the Commission’s annually approved Controlled Therapeutic Medication List are not to be used in a manner inconsistent with the restrictions contained therein. NSAIDs not included on the Commission’s Controlled Therapeutic Medication List are not to be present in a racing horse biological test sample at the laboratory concentration of detection.
(b) The presence of more than one NSAID may constitute a NSAID stacking violation consistent with the following restrictions:
(1) A Class 1 NSAID Stacking Violation (Penalty Class B) occurs when:
(i) Two Non-Steroidal Anti-Inflammatory drugs are found at individual levels determined to exceed the following restrictions:
(a) Diclofenac—5 nanograms per milliliter of plasma or serum;
(b) Firocoxib—20 nanograms per milliliter of plasma or serum;
(c) Flunixin—20 nanograms per milliliter of plasma or serum;
(d) Ketoprofen—2 nanograms per milliliter of plasma or serum;
(e) Phenylbutazone—2 micrograms per milliliter of plasma or serum; or
(f) All other Non-Steroidal Anti-Inflammatory drugs—laboratory concentration of detection.
(ii) Three or more Non-Steroidal Anti-Inflammatory drugs are found at individual levels determined to exceed the following restrictions:
(a) Diclofenac—5 nanograms per milliliter of plasma or serum;
(b) Firocoxib—20 nanograms per milliliter of plasma or serum;
(c) Flunixin—3 nanograms per milliliter of plasma or serum;
(d) Ketoprofen—1 nanograms per milliliter of plasma or serum;
(e) Phenylbutazone—0.3 micrograms per milliliter of plasma or serum; or
(f) All other Non-Steroidal Anti-Inflammatory drugs—laboratory concentration of detection.
(2) A Class 2 NSAID Stacking Violation (Penalty Class C) occurs when:
(i) Any one substance noted in subsection (b)(1) is found in excess of the restrictions contained therein in combination with any one of the following substances at levels below the restrictions so noted but in excess of the following levels:
(a) Flunixin—3 nanograms per milliliter of plasma or serum;
(b) Ketoprofen—1 nanogram per milliliter of plasma or serum; or
(c) Phenylbutazone—0.3 micrograms per milliliter of plasma or serum.
(3) A Class 3 NSAID Stacking Violation (Penalty Class C, fines only) occurs when:
(i) Any combination of two of the following Non-Steroidal Anti-Inflammatory drugs are found at or below the restrictions in subsection (b)(1)(i), but in excess of the noted restrictions:
(a) Flunixin—3 nanograms per milliliter of plasma or serum;
(b) Ketoprofen—1 nanogram per milliliter of plasma or serum; or
(c) Phenylbutazone—0.3 micrograms per milliliter of plasma or serum;
(c) Any horse to which a NSAID has been administered shall be subject to having a blood or urine samples, or both, taken at the direction of the Commission Veterinarian to determine the quantitative NSAID levels or the presence of other drugs, or both, which may be present in the blood or urine samples.
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